Poly(ADP-ribose)polymerase 1 stimulates the AP-site cleavage activity of tyrosyl-DNA phosphodiesterase 1

The influence of poly(ADP-ribose)polymerase 1 (PARP1) on the apurinic/apyrimidinic (AP)-site cleavage activity of tyrosyl–DNA phosphodiesterase 1 (TDP1) and interaction of PARP1 and TDP1 were studied. The efficiency of single or clustered AP-site hydrolysis catalysed by TDP1 was estimated. It was sh...

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Detalles Bibliográficos
Autores principales: Lebedeva, Natalia A., Anarbaev, Rashid O., Sukhanova, Maria, Vasil’eva, Inna A., Rechkunova, Nadejda I., Lavrik, Olga I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2015
Materias:
Original Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4721542/
https://www.ncbi.nlm.nih.gov/pubmed/26181362
http://dx.doi.org/10.1042/BSR20140192

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4721542/
https://www.ncbi.nlm.nih.gov/pubmed/26181362
http://dx.doi.org/10.1042/BSR20140192

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