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Dynamics and Determinants of Pneumococcal Antibodies Specific against 13 Vaccine Serotypes in the Pre-Vaccination Era

INTRODUCTION: Introduction of pneumococcal conjugate vaccines (PCVs) for infants decreased overall invasive pneumococcal disease (IPD), while non-vaccine serotype IPD increased. To fully understand this serotype replacement, knowledge about serotype dynamics in the pre-vaccine era is needed. In addi...

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Detalles Bibliográficos
Autores principales: Prins-van Ginkel, Annemarijn C., Berbers, Guy A. M., Grundeken, Lucienne H., Tcherniaeva, Irina, Wittenberns, Jelle I., Elberse, Karin, Mollema, Liesbeth, de Melker, Hester E., Knol, Mirjam J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4721864/
https://www.ncbi.nlm.nih.gov/pubmed/26796783
http://dx.doi.org/10.1371/journal.pone.0147437