Neuroinvasive West Nile Infection Elicits Elevated and Atypically Polarized T Cell Responses That Promote a Pathogenic Outcome

Most West Nile virus (WNV) infections are asymptomatic, but some lead to neuroinvasive disease with symptoms ranging from disorientation to paralysis and death. Evidence from animal models suggests that neuroinvasive infections may arise as a consequence of impaired immune protection. However, other...

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Detalles Bibliográficos
Autores principales: James, Eddie A., Gates, Theresa J., LaFond, Rebecca E., Yamamoto, Shinobu, Ni, Chester, Mai, Duy, Gersuk, Vivian H., O’Brien, Kimberly, Nguyen, Quynh-Anh, Zeitner, Brad, Lanteri, Marion C., Norris, Philip J., Chaussabel, Damien, Malhotra, Uma, Kwok, William W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4721872/
https://www.ncbi.nlm.nih.gov/pubmed/26795118
http://dx.doi.org/10.1371/journal.ppat.1005375

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