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Brief low [Mg(2+)](o)-induced Ca(2+) spikes inhibit subsequent prolonged exposure-induced excitotoxicity in cultured rat hippocampal neurons
Reducing [Mg(2+)](o) to 0.1 mM can evoke repetitive [Ca(2+)](i) spikes and seizure activity, which induces neuronal cell death in a process called excitotoxicity. We examined the issue of whether cultured rat hippocampal neurons preconditioned by a brief exposure to 0.1 mM [Mg(2+)](o) are rendered r...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Korean Physiological Society and The Korean Society of Pharmacology
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4722183/ https://www.ncbi.nlm.nih.gov/pubmed/26807029 http://dx.doi.org/10.4196/kjpp.2016.20.1.101 |