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Inducibility of human atrial fibrillation in an in silico model reflecting local acetylcholine distribution and concentration

Vagal nerve activity has been known to play a crucial role in the induction and maintenance of atrial fibrillation (AF). However, it is unclear how the distribution and concentration of local acetylcholine (ACh) promotes AF. In this study, we investigated the effect of the spatial distribution and c...

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Detalles Bibliográficos
Autores principales: Hwang, Minki, Lee, Hyun-Seung, Pak, Hui-Nam, Shim, Eun Bo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Physiological Society and The Korean Society of Pharmacology 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4722184/
https://www.ncbi.nlm.nih.gov/pubmed/26807030
http://dx.doi.org/10.4196/kjpp.2016.20.1.111