Carnosic acid protects against acetaminophen-induced hepatotoxicity by potentiating Nrf2-mediated antioxidant capacity in mice

Acetaminophen (APAP) overdose is one of the most common causes of acute liver failure. The study aimed to investigate the protective effect of carnosic acid (CA) on APAP-induced acute hepatotoxicity and its underlying mechanism in mice. To induce hepatotoxicity, APAP solution (400 mg/kg) was adminis...

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Detalles Bibliográficos
Autores principales: Guo, Qi, Shen, Zhiyang, Yu, Hongxia, Lu, Gaofeng, Yu, Yong, Liu, Xia, Zheng, Pengyuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Physiological Society and The Korean Society of Pharmacology 2016
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4722187/
https://www.ncbi.nlm.nih.gov/pubmed/26807019
http://dx.doi.org/10.4196/kjpp.2016.20.1.15

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4722187/
https://www.ncbi.nlm.nih.gov/pubmed/26807019
http://dx.doi.org/10.4196/kjpp.2016.20.1.15

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