A Case Series of Acquired Drug Resistance-Associated Mutations in Human Immunodeficiency Virus-Infected Children: An Emerging Public Health Concern in Rural Africa

The acquisition of drug-resistance mutations among African children living with in human immunodeficiency virus on antiretroviral treatment has been scarcely reported. This threatens the overall success of antiretroviral programs and the clinical outcomes of children in care. We present a well chara...

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Autores principales: Gamell, Anna, Muri, Lukas, Ntamatungiro, Alex, Nyogea, Daniel, Luwanda, Lameck B., Hatz, Christoph, Battegay, Manuel, Felger, Ingrid, Tanner, Marcel, Klimkait, Thomas, Letang, Emilio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Brief Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4722282/
https://www.ncbi.nlm.nih.gov/pubmed/26807427
http://dx.doi.org/10.1093/ofid/ofv199
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author Gamell, Anna
Muri, Lukas
Ntamatungiro, Alex
Nyogea, Daniel
Luwanda, Lameck B.
Hatz, Christoph
Battegay, Manuel
Felger, Ingrid
Tanner, Marcel
Klimkait, Thomas
Letang, Emilio
author_facet Gamell, Anna
Muri, Lukas
Ntamatungiro, Alex
Nyogea, Daniel
Luwanda, Lameck B.
Hatz, Christoph
Battegay, Manuel
Felger, Ingrid
Tanner, Marcel
Klimkait, Thomas
Letang, Emilio
author_sort Gamell, Anna
collection PubMed
description The acquisition of drug-resistance mutations among African children living with in human immunodeficiency virus on antiretroviral treatment has been scarcely reported. This threatens the overall success of antiretroviral programs and the clinical outcomes of children in care. We present a well characterized series of children from rural Tanzania with acquired drug-resistance mutations to contribute to the better understanding of this emerging public health concern.
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spelling pubmed-47222822016-01-22 A Case Series of Acquired Drug Resistance-Associated Mutations in Human Immunodeficiency Virus-Infected Children: An Emerging Public Health Concern in Rural Africa Gamell, Anna Muri, Lukas Ntamatungiro, Alex Nyogea, Daniel Luwanda, Lameck B. Hatz, Christoph Battegay, Manuel Felger, Ingrid Tanner, Marcel Klimkait, Thomas Letang, Emilio Open Forum Infect Dis Brief Reports The acquisition of drug-resistance mutations among African children living with in human immunodeficiency virus on antiretroviral treatment has been scarcely reported. This threatens the overall success of antiretroviral programs and the clinical outcomes of children in care. We present a well characterized series of children from rural Tanzania with acquired drug-resistance mutations to contribute to the better understanding of this emerging public health concern. Oxford University Press 2015-12-17 /pmc/articles/PMC4722282/ /pubmed/26807427 http://dx.doi.org/10.1093/ofid/ofv199 Text en © The Author 2015. Published by Oxford University Press on behalf of the Infectious Diseases Society of America. http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs licence (http://creativecommons.org/licenses/by-nc-nd/4.0/), which permits non-commercial reproduction and distribution of the work, in any medium, provided the original work is not altered or transformed in any way, and that the work is properly cited. For commercial re-use, please contact journals.permissions@oup.com.
spellingShingle Brief Reports
Gamell, Anna
Muri, Lukas
Ntamatungiro, Alex
Nyogea, Daniel
Luwanda, Lameck B.
Hatz, Christoph
Battegay, Manuel
Felger, Ingrid
Tanner, Marcel
Klimkait, Thomas
Letang, Emilio
A Case Series of Acquired Drug Resistance-Associated Mutations in Human Immunodeficiency Virus-Infected Children: An Emerging Public Health Concern in Rural Africa
title A Case Series of Acquired Drug Resistance-Associated Mutations in Human Immunodeficiency Virus-Infected Children: An Emerging Public Health Concern in Rural Africa
title_full A Case Series of Acquired Drug Resistance-Associated Mutations in Human Immunodeficiency Virus-Infected Children: An Emerging Public Health Concern in Rural Africa
title_fullStr A Case Series of Acquired Drug Resistance-Associated Mutations in Human Immunodeficiency Virus-Infected Children: An Emerging Public Health Concern in Rural Africa
title_full_unstemmed A Case Series of Acquired Drug Resistance-Associated Mutations in Human Immunodeficiency Virus-Infected Children: An Emerging Public Health Concern in Rural Africa
title_short A Case Series of Acquired Drug Resistance-Associated Mutations in Human Immunodeficiency Virus-Infected Children: An Emerging Public Health Concern in Rural Africa
title_sort case series of acquired drug resistance-associated mutations in human immunodeficiency virus-infected children: an emerging public health concern in rural africa
topic Brief Reports
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4722282/
https://www.ncbi.nlm.nih.gov/pubmed/26807427
http://dx.doi.org/10.1093/ofid/ofv199
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