Monitoring Ras Interactions with the Nucleotide Exchange Factor Son of Sevenless (Sos) Using Site-specific NMR Reporter Signals and Intrinsic Fluorescence

The activity of Ras is controlled by the interconversion between GTP- and GDP-bound forms partly regulated by the binding of the guanine nucleotide exchange factor Son of Sevenless (Sos). The details of Sos binding, leading to nucleotide exchange and subsequent dissociation of the complex, are not c...

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Detalles Bibliográficos
Autores principales: Vo, Uybach, Vajpai, Navratna, Flavell, Liz, Bobby, Romel, Breeze, Alexander L., Embrey, Kevin J., Golovanov, Alexander P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2016
Materias:
Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4722452/
https://www.ncbi.nlm.nih.gov/pubmed/26565026
http://dx.doi.org/10.1074/jbc.M115.691238

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4722452/
https://www.ncbi.nlm.nih.gov/pubmed/26565026
http://dx.doi.org/10.1074/jbc.M115.691238

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