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Adamantinoma of the Tibia: A Case Report

INTRODUCTION: Adamantinoma is a bone tumor which is commonly showed in mandible. Its occurrence in long bones constitutes a rare affection and a difficult histological diagnosis This rare malignant tumor of mesenchymal and epithelial origin was discovered in the tibia of a male patient. CASE REPORT:...

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Autores principales: Anoumou, Michel N., Kouameu, Maurice, Koffi, Emmanuel K., Varango, Guy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Indian Orthopaedic Research Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4722559/
https://www.ncbi.nlm.nih.gov/pubmed/27298937
http://dx.doi.org/10.13107/jocr.2250-0685.140
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author Anoumou, Michel N.
Kouameu, Maurice
Koffi, Emmanuel K.
Varango, Guy
author_facet Anoumou, Michel N.
Kouameu, Maurice
Koffi, Emmanuel K.
Varango, Guy
author_sort Anoumou, Michel N.
collection PubMed
description INTRODUCTION: Adamantinoma is a bone tumor which is commonly showed in mandible. Its occurrence in long bones constitutes a rare affection and a difficult histological diagnosis This rare malignant tumor of mesenchymal and epithelial origin was discovered in the tibia of a male patient. CASE REPORT: The authors report a case of adamantinoma of the tibia in a 36- years old. He presented with slowly progressing leg swelling that evolved over 2 years without significant clinical manifestation. Complementary examination and investigation did not help in differential diagnosis and confirmation was only possible after histological examination. There was increase in size of lesion with increased pain and patie3nt presented with pathological fracture. Local extension of the tumor indicated an amputation of leg. The histological exam of the amputation specimen confirmed the results of the initial biopsy by showing cells tumorales in favour of an adamantinoma. After a good medium-term follow up, the patient died secondary to lung metastases. The authors discuss their method of diagnosis and therapeutics in front of such tumor. CONCLUSION: Adamantinoma is characterized by a slow clinical development marked by the prevalence of lung metastases and local recurrences. After the diagnosis, there must be a complete and sufficient surgery to avoid a local recurrence or metastasis.
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spelling pubmed-47225592016-06-13 Adamantinoma of the Tibia: A Case Report Anoumou, Michel N. Kouameu, Maurice Koffi, Emmanuel K. Varango, Guy J Orthop Case Reports Case Report INTRODUCTION: Adamantinoma is a bone tumor which is commonly showed in mandible. Its occurrence in long bones constitutes a rare affection and a difficult histological diagnosis This rare malignant tumor of mesenchymal and epithelial origin was discovered in the tibia of a male patient. CASE REPORT: The authors report a case of adamantinoma of the tibia in a 36- years old. He presented with slowly progressing leg swelling that evolved over 2 years without significant clinical manifestation. Complementary examination and investigation did not help in differential diagnosis and confirmation was only possible after histological examination. There was increase in size of lesion with increased pain and patie3nt presented with pathological fracture. Local extension of the tumor indicated an amputation of leg. The histological exam of the amputation specimen confirmed the results of the initial biopsy by showing cells tumorales in favour of an adamantinoma. After a good medium-term follow up, the patient died secondary to lung metastases. The authors discuss their method of diagnosis and therapeutics in front of such tumor. CONCLUSION: Adamantinoma is characterized by a slow clinical development marked by the prevalence of lung metastases and local recurrences. After the diagnosis, there must be a complete and sufficient surgery to avoid a local recurrence or metastasis. Indian Orthopaedic Research Group 2014 /pmc/articles/PMC4722559/ /pubmed/27298937 http://dx.doi.org/10.13107/jocr.2250-0685.140 Text en Copyright: © Indian Orthopaedic Research Group http://creativecommons.org/licenses/by-nc-sa/3.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc-sa/3.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Anoumou, Michel N.
Kouameu, Maurice
Koffi, Emmanuel K.
Varango, Guy
Adamantinoma of the Tibia: A Case Report
title Adamantinoma of the Tibia: A Case Report
title_full Adamantinoma of the Tibia: A Case Report
title_fullStr Adamantinoma of the Tibia: A Case Report
title_full_unstemmed Adamantinoma of the Tibia: A Case Report
title_short Adamantinoma of the Tibia: A Case Report
title_sort adamantinoma of the tibia: a case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4722559/
https://www.ncbi.nlm.nih.gov/pubmed/27298937
http://dx.doi.org/10.13107/jocr.2250-0685.140
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