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Anti-fatigue effect of Amarkand on endurance exercise capacity in rats
BACKGROUND: Amarkand tubers are routinely used by many Indian tribes as a specialized food for health and longevity but so far there is no scientific evidence for their activities. Taxonomically, Amarkand belong to genera Eulophia and Dioscorea. METHODS: In this communication, comparative antifatigu...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4722617/ https://www.ncbi.nlm.nih.gov/pubmed/26801757 http://dx.doi.org/10.1186/s12906-016-0995-2 |
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author | Narkhede, Aarti N. Jagtap, Suresh D. Nirmal, Pallavi S. Giramkar, Shital A. Nagarkar, Bhagyashri E. Kulkarni, Omkar P. Harsulkar, Abhay M. |
author_facet | Narkhede, Aarti N. Jagtap, Suresh D. Nirmal, Pallavi S. Giramkar, Shital A. Nagarkar, Bhagyashri E. Kulkarni, Omkar P. Harsulkar, Abhay M. |
author_sort | Narkhede, Aarti N. |
collection | PubMed |
description | BACKGROUND: Amarkand tubers are routinely used by many Indian tribes as a specialized food for health and longevity but so far there is no scientific evidence for their activities. Taxonomically, Amarkand belong to genera Eulophia and Dioscorea. METHODS: In this communication, comparative antifatigue potential of Amarkand was analyzed using forced swimming model in rats and evaluated using biomarkers of physical fatigue. RESULTS: Methanol extracts of tubers of D. bulbifera, E. ochreata, E. leghapanensis and bulbils of D. bulbifera exhibited rich polyphenolic content. D. bulbifera bulbils and E. ochreata significantly prolonged the swimming endurance time. Creatine kinase and urea nitrogen were significantly reduced by treatment of D. bulbifera bulbils and E. ochreata as compared to negative control. D. bulbifera bulbils effectively increased creatine (p < 0.001), lactate dehydrogenase (p < 0.01) and hemoglobin (p < 0.001) compared to negative control. D. bulbifera bulbils and E. ochreata treatments significantly increased glycogen (p < 0.05, p < 0.01) and lowered malondialdehyde levels (p < 0.001) in muscles and in liver tissue compared to negative control. CONCLUSION: These results indicate that a treatment with D. bulbifera bulbils and tubers of E. ochreata facilitates aerobic glucose metabolism and endurance by improving various impairments associated with fatigue. |
format | Online Article Text |
id | pubmed-4722617 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2016 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-47226172016-01-23 Anti-fatigue effect of Amarkand on endurance exercise capacity in rats Narkhede, Aarti N. Jagtap, Suresh D. Nirmal, Pallavi S. Giramkar, Shital A. Nagarkar, Bhagyashri E. Kulkarni, Omkar P. Harsulkar, Abhay M. BMC Complement Altern Med Research Article BACKGROUND: Amarkand tubers are routinely used by many Indian tribes as a specialized food for health and longevity but so far there is no scientific evidence for their activities. Taxonomically, Amarkand belong to genera Eulophia and Dioscorea. METHODS: In this communication, comparative antifatigue potential of Amarkand was analyzed using forced swimming model in rats and evaluated using biomarkers of physical fatigue. RESULTS: Methanol extracts of tubers of D. bulbifera, E. ochreata, E. leghapanensis and bulbils of D. bulbifera exhibited rich polyphenolic content. D. bulbifera bulbils and E. ochreata significantly prolonged the swimming endurance time. Creatine kinase and urea nitrogen were significantly reduced by treatment of D. bulbifera bulbils and E. ochreata as compared to negative control. D. bulbifera bulbils effectively increased creatine (p < 0.001), lactate dehydrogenase (p < 0.01) and hemoglobin (p < 0.001) compared to negative control. D. bulbifera bulbils and E. ochreata treatments significantly increased glycogen (p < 0.05, p < 0.01) and lowered malondialdehyde levels (p < 0.001) in muscles and in liver tissue compared to negative control. CONCLUSION: These results indicate that a treatment with D. bulbifera bulbils and tubers of E. ochreata facilitates aerobic glucose metabolism and endurance by improving various impairments associated with fatigue. BioMed Central 2016-01-22 /pmc/articles/PMC4722617/ /pubmed/26801757 http://dx.doi.org/10.1186/s12906-016-0995-2 Text en © Narkhede et al. 2016 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated. |
spellingShingle | Research Article Narkhede, Aarti N. Jagtap, Suresh D. Nirmal, Pallavi S. Giramkar, Shital A. Nagarkar, Bhagyashri E. Kulkarni, Omkar P. Harsulkar, Abhay M. Anti-fatigue effect of Amarkand on endurance exercise capacity in rats |
title | Anti-fatigue effect of Amarkand on endurance exercise capacity in rats |
title_full | Anti-fatigue effect of Amarkand on endurance exercise capacity in rats |
title_fullStr | Anti-fatigue effect of Amarkand on endurance exercise capacity in rats |
title_full_unstemmed | Anti-fatigue effect of Amarkand on endurance exercise capacity in rats |
title_short | Anti-fatigue effect of Amarkand on endurance exercise capacity in rats |
title_sort | anti-fatigue effect of amarkand on endurance exercise capacity in rats |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4722617/ https://www.ncbi.nlm.nih.gov/pubmed/26801757 http://dx.doi.org/10.1186/s12906-016-0995-2 |
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