Clinical evaluation of panel testing by next-generation sequencing (NGS) for gene mutations in myeloid neoplasms

BACKGROUND: Genomic techniques in recent years have allowed the identification of many mutated genes important in the pathogenesis of acute myeloid leukemia (AML). Together with cytogenetic aberrations, these gene mutations are powerful prognostic markers in AML and can be used to guide patient mana...

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Detalles Bibliográficos
Autores principales: Au, Chun Hang, Wa, Anna, Ho, Dona N., Chan, Tsun Leung, Ma, Edmond S. K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4722624/
https://www.ncbi.nlm.nih.gov/pubmed/26796102
http://dx.doi.org/10.1186/s13000-016-0456-8

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