Lack of K13 mutations in Plasmodium falciparum persisting after artemisinin combination therapy treatment of Kenyan children

BACKGROUND: Studies in Southeast Asia reported a strong relationship between polymorphisms at the propeller domain of the Kelch 13 (K13) protein encoded by the Plasmodiumfalciparumk13(pfk13) gene and delayed parasite clearance after artemisinin treatment. In Africa, P. falciparum remains susceptible...

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Detalles Bibliográficos
Autores principales: Muwanguzi, Julian, Henriques, Gisela, Sawa, Patrick, Bousema, Teun, Sutherland, Colin J., Beshir, Khalid B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4722670/
https://www.ncbi.nlm.nih.gov/pubmed/26801909
http://dx.doi.org/10.1186/s12936-016-1095-y

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