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SSTR2 promoter hypermethylation is associated with the risk and progression of laryngeal squamous cell carcinoma in males

BACKGROUND: Somatostatin receptor 2 (SSTR2) encodes somatostatin receptor that can inhibit the cell proliferation of solid tumors. Promoter hypermethylation is likely to silence the expression of SSTR2. The goal of our study was to investigate the association between SSTR2 promoter methylation and t...

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Detalles Bibliográficos
Autores principales: Shen, Zhisen, Chen, Xiaoying, Li, Qun, Zhou, Chongchang, Li, Jinyun, Ye, Huadan, Duan, Shiwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4722764/
https://www.ncbi.nlm.nih.gov/pubmed/26796520
http://dx.doi.org/10.1186/s13000-016-0461-y