AMPK-Activated Protein Kinase Suppresses Ccr2 Expression by Inhibiting the NF-κB Pathway in RAW264.7 Macrophages

C-C chemokine receptor 2 (Ccr2) is a key pro-inflammatory marker of classic (M1) macrophage activation. Although Ccr2 is known to be expressed both constitutively and inductively, the full regulatory mechanism of its expression remains unclear. AMP-activated protein kinase (AMPK) is not only a maste...

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Detalles Bibliográficos
Autores principales: Kumase, Fumiaki, Takeuchi, Kimio, Morizane, Yuki, Suzuki, Jun, Matsumoto, Hidetaka, Kataoka, Keiko, Al-Moujahed, Ahmad, Maidana, Daniel E., Miller, Joan W., Vavvas, Demetrios G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4723067/
https://www.ncbi.nlm.nih.gov/pubmed/26799633
http://dx.doi.org/10.1371/journal.pone.0147279

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