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PCSK9 Plasma Concentrations Are Independent of GFR and Do Not Predict Cardiovascular Events in Patients with Decreased GFR

BACKGROUND: Impaired renal function causes dyslipidemia that contributes to elevated cardiovascular risk in patients with chronic kidney disease (CKD). The proprotein convertase subtilisin/kexin type 9 (PCSK9) is a regulator of the LDL receptor and plasma cholesterol concentrations. Its relationship...

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Detalles Bibliográficos
Autores principales:	Rogacev, Kyrill S., Heine, Gunnar H., Silbernagel, Günther, Kleber, Marcus E., Seiler, Sarah, Emrich, Insa, Lennartz, Simone, Werner, Christian, Zawada, Adam M., Fliser, Danilo, Böhm, Michael, März, Winfried, Scharnagl, Hubert, Laufs, Ulrich
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4723078/ https://www.ncbi.nlm.nih.gov/pubmed/26799206 http://dx.doi.org/10.1371/journal.pone.0146920

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