Molecular Dissection of Induced Platinum Resistance through Functional and Gene Expression Analysis in a Cell Culture Model of Bladder Cancer

We report herein the development, functional and molecular characterization of an isogenic, paired bladder cancer cell culture model system for studying platinum drug resistance. The 5637 human bladder cancer cell line was cultured over ten months with stepwise increases in oxaliplatin concentration...

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Detalles Bibliográficos
Autores principales: Wang, Sisi, Zhang, Hongyong, Scharadin, Tiffany M., Zimmermann, Maike, Hu, Bin, Pan, Amy Wang, Vinall, Ruth, Lin, Tzu-yin, Cimino, George, Chain, Patrick, Vuyisich, Momchilo, Gleasner, Cheryl, Mcmurry, Kim, Malfatti, Michael, Turteltaub, Kenneth, de Vere White, Ralph, Pan, Chong-xian, Henderson, Paul T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4723083/
https://www.ncbi.nlm.nih.gov/pubmed/26799320
http://dx.doi.org/10.1371/journal.pone.0146256

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4723083/
https://www.ncbi.nlm.nih.gov/pubmed/26799320
http://dx.doi.org/10.1371/journal.pone.0146256

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