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Molecular Dissection of Induced Platinum Resistance through Functional and Gene Expression Analysis in a Cell Culture Model of Bladder Cancer
We report herein the development, functional and molecular characterization of an isogenic, paired bladder cancer cell culture model system for studying platinum drug resistance. The 5637 human bladder cancer cell line was cultured over ten months with stepwise increases in oxaliplatin concentration...
Autores principales: | Wang, Sisi, Zhang, Hongyong, Scharadin, Tiffany M., Zimmermann, Maike, Hu, Bin, Pan, Amy Wang, Vinall, Ruth, Lin, Tzu-yin, Cimino, George, Chain, Patrick, Vuyisich, Momchilo, Gleasner, Cheryl, Mcmurry, Kim, Malfatti, Michael, Turteltaub, Kenneth, de Vere White, Ralph, Pan, Chong-xian, Henderson, Paul T. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4723083/ https://www.ncbi.nlm.nih.gov/pubmed/26799320 http://dx.doi.org/10.1371/journal.pone.0146256 |
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