A local renal renin–angiotensin system activation via renal uptake of prorenin and angiotensinogen in diabetic rats

The mechanism of activation of local renal renin–angiotensin system (RAS) has not been clarified in diabetes mellitus (DM). We hypothesized that the local renal RAS will be activated via increased glomerular filtration and tubular uptake of prorenin and angiotensinogen in diabetic kidney with microa...

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Detalles Bibliográficos
Autores principales: Tojo, Akihiro, Kinugasa, Satoshi, Fujita, Toshiro, Wilcox, Christopher S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2016
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4723098/
https://www.ncbi.nlm.nih.gov/pubmed/26848273
http://dx.doi.org/10.2147/DMSO.S91245

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4723098/
https://www.ncbi.nlm.nih.gov/pubmed/26848273
http://dx.doi.org/10.2147/DMSO.S91245

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