Primary Biliary Cirrhosis Overlapping with Autoimmune Hepatitis in an HIV-Infected Patient on Antiretroviral Therapy

Liver disease in HIV-infected patients is complex and multifactorial. Drug toxicity and infections are common causes of elevations in liver-associated enzymes. Immune reconstitution and unmasking of autoimmune disease may also play a role, particularly in the era of effective combination antiretrovi...

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Autores principales: Caplan, Margaret, Trivedi, Apurva, McLaughlin, Mary, Hebou, Annick, Kleiner, David E., Heller, Theo, Morse, Caryn G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4723101/
https://www.ncbi.nlm.nih.gov/pubmed/26807302
http://dx.doi.org/10.5455/jihp.20130624104921
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author Caplan, Margaret
Trivedi, Apurva
McLaughlin, Mary
Hebou, Annick
Kleiner, David E.
Heller, Theo
Morse, Caryn G.
author_facet Caplan, Margaret
Trivedi, Apurva
McLaughlin, Mary
Hebou, Annick
Kleiner, David E.
Heller, Theo
Morse, Caryn G.
author_sort Caplan, Margaret
collection PubMed
description Liver disease in HIV-infected patients is complex and multifactorial. Drug toxicity and infections are common causes of elevations in liver-associated enzymes. Immune reconstitution and unmasking of autoimmune disease may also play a role, particularly in the era of effective combination antiretroviral therapy. In this case report, we describe the first reported biopsy-confirmed case of autoimmune hepatitis and primary biliary cirrhosis overlap syndrome presenting in an HIV-infected patient following initiation of antiretroviral therapy.
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spelling pubmed-47231012016-01-22 Primary Biliary Cirrhosis Overlapping with Autoimmune Hepatitis in an HIV-Infected Patient on Antiretroviral Therapy Caplan, Margaret Trivedi, Apurva McLaughlin, Mary Hebou, Annick Kleiner, David E. Heller, Theo Morse, Caryn G. J Interdiscip Histopathol Article Liver disease in HIV-infected patients is complex and multifactorial. Drug toxicity and infections are common causes of elevations in liver-associated enzymes. Immune reconstitution and unmasking of autoimmune disease may also play a role, particularly in the era of effective combination antiretroviral therapy. In this case report, we describe the first reported biopsy-confirmed case of autoimmune hepatitis and primary biliary cirrhosis overlap syndrome presenting in an HIV-infected patient following initiation of antiretroviral therapy. 2013-06-30 2013 /pmc/articles/PMC4723101/ /pubmed/26807302 http://dx.doi.org/10.5455/jihp.20130624104921 Text en http://creativecommons.org/licenses/by/4.0/ This is an open access article licensed under the terms of the Creative Commons Attribution Non-Commercial License which permits unrestricted, non-commercial use, distribution and reproduction in any medium, provided the work is properly cited.
spellingShingle Article
Caplan, Margaret
Trivedi, Apurva
McLaughlin, Mary
Hebou, Annick
Kleiner, David E.
Heller, Theo
Morse, Caryn G.
Primary Biliary Cirrhosis Overlapping with Autoimmune Hepatitis in an HIV-Infected Patient on Antiretroviral Therapy
title Primary Biliary Cirrhosis Overlapping with Autoimmune Hepatitis in an HIV-Infected Patient on Antiretroviral Therapy
title_full Primary Biliary Cirrhosis Overlapping with Autoimmune Hepatitis in an HIV-Infected Patient on Antiretroviral Therapy
title_fullStr Primary Biliary Cirrhosis Overlapping with Autoimmune Hepatitis in an HIV-Infected Patient on Antiretroviral Therapy
title_full_unstemmed Primary Biliary Cirrhosis Overlapping with Autoimmune Hepatitis in an HIV-Infected Patient on Antiretroviral Therapy
title_short Primary Biliary Cirrhosis Overlapping with Autoimmune Hepatitis in an HIV-Infected Patient on Antiretroviral Therapy
title_sort primary biliary cirrhosis overlapping with autoimmune hepatitis in an hiv-infected patient on antiretroviral therapy
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4723101/
https://www.ncbi.nlm.nih.gov/pubmed/26807302
http://dx.doi.org/10.5455/jihp.20130624104921
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