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Alemtuzumab long-term immunologic effect: Treg suppressor function increases up to 24 months
OBJECTIVE: To analyze changes in T-helper (Th) subsets, T-regulatory (Treg) cell percentages and function, and mRNA levels of immunologically relevant molecules during a 24-month follow-up after alemtuzumab treatment in patients with relapsing-remitting multiple sclerosis (RRMS). METHODS: Multicente...
Autores principales: | De Mercanti, Stefania, Rolla, Simona, Cucci, Angele, Bardina, Valentina, Cocco, Eleonora, Vladic, Anton, Soldo-Butkovic, Silva, Habek, Mario, Adamec, Ivan, Horakova, Dana, Annovazzi, Pietro, Novelli, Francesco, Durelli, Luca, Clerico, Marinella |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Lippincott Williams & Wilkins
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4723135/ https://www.ncbi.nlm.nih.gov/pubmed/26819963 http://dx.doi.org/10.1212/NXI.0000000000000194 |
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