Cargando…
A Viral microRNA Cluster Regulates the Expression of PTEN, p27 and of a bcl-2 Homolog
The Epstein-Barr virus (EBV) infects and transforms B-lymphocytes with high efficiency. This process requires expression of the viral latent proteins and of the 3 miR-BHRF1 microRNAs. Here we show that B-cells infected by a virus that lacks these non-coding RNAs (Δ123) grew more slowly between day 5...
| Autores principales: | , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2016
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4723338/ https://www.ncbi.nlm.nih.gov/pubmed/26800049 http://dx.doi.org/10.1371/journal.ppat.1005405 |