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Targeted antitumor prodrug therapy using CNGRC-yCD fusion protein in combination with 5-fluorocytosine

BACKGROUND: The enzyme-prodrug system is considered a promising tool for tumor treatment when conjugated with a targeting molecule. The asparagine-glycine-arginine (NGR) motif is a developing and interesting targeting peptide that could specifically bind to aminopeptidase N (APN), which is an NGR re...

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Detalles Bibliográficos
Autores principales:	Li, Jia-Je, Chang, Shun-Fu, Liau, I-Iu, Chan, Pei-Chia, Liu, Ren-Shyan, Yen, Sang-Hue, Wang, Hsin-Ell, Chang, Cheng Allen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2016
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4724154/ https://www.ncbi.nlm.nih.gov/pubmed/26801910 http://dx.doi.org/10.1186/s12929-016-0227-6

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