Cargando…
Anti-RANKL treatment inhibits erosive joint destruction and lowers inflammation but has no effect on bone formation in the delayed-type hypersensitivity arthritis (DTHA) model
BACKGROUND: The aims of the present study were to determine the relationship between bone destruction and bone formation in the delayed-type hypersensitivity arthritis (DTHA) model and to evaluate the effect of receptor activator of nuclear factor κB ligand (RANKL) blockade on severity of arthritis,...
Autores principales: | Atkinson, Sara Marie, Bleil, Janine, Maier, René, Kühl, Anja A., Thorn, Mette, Serikawa, Kyle, Fox, Brian, Kruse, Kim, Haase, Claus, Skov, Søren, Nansen, Anneline, Syrbe, Uta |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4724155/ https://www.ncbi.nlm.nih.gov/pubmed/26801240 http://dx.doi.org/10.1186/s13075-016-0931-3 |
Ejemplares similares
-
Depletion of regulatory T cells leads to an exacerbation of delayed-type hypersensitivity arthritis in C57BL/6 mice that can be counteracted by IL-17 blockade
por: Atkinson, Sara Marie, et al.
Publicado: (2016) -
Establishment and characterization of a sustained delayed-type hypersensitivity model with arthritic manifestations in C57BL/6J mice
por: Atkinson, Sara M, et al.
Publicado: (2012) -
Cartilage in facet joints of patients with ankylosing spondylitis (AS) shows signs of cartilage degeneration rather than chondrocyte hypertrophy: implications for joint remodeling in AS
por: Bleil, Janine, et al.
Publicado: (2015) -
Activated, Pro-Inflammatory Th1, Th17, and Memory CD4+ T Cells and B Cells Are Involved in Delayed-Type Hypersensitivity Arthritis (DTHA) Inflammation and Paw Swelling in Mice
por: Li, Gaoyang, et al.
Publicado: (2021) -
Regulation of RANKL signaling in arthritic bone destruction
por: Takayanagi, H
Publicado: (2003)