Brain-derived neurotrophic factor genetic polymorphism (rs6265) is protective against chemotherapy-associated cognitive impairment in patients with early-stage breast cancer

BACKGROUND: Brain-derived neurotrophic factor (BDNF), a neurotrophin that regulates neuronal function and development, is implicated in several neurodegenerative conditions. Preliminary data suggest that a reduction of BDNF concentrations may lead to postchemotherapy cognitive impairment. We hypothe...

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Detalles Bibliográficos
Autores principales: Ng, Terence, Teo, Shu Mei, Yeo, Hui Ling, Shwe, Maung, Gan, Yan Xiang, Cheung, Yin Ting, Foo, Koon Mian, Cham, Mooi Tai, Lee, Jung Ah, Tan, Yee Pin, Fan, Gilbert, Yong, Wei Sean, Preetha, Madhukumar, Loh, Wei-Jen Kiley, Koo, Si-Lin, Jain, Amit, Lee, Guek Eng, Wong, Mabel, Dent, Rebecca, Yap, Yoon Sim, Ng, Raymond, Khor, Chiea Chuen, Ho, Han Kiat, Chan, Alexandre
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Clinical Investigations
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4724179/
https://www.ncbi.nlm.nih.gov/pubmed/26289590
http://dx.doi.org/10.1093/neuonc/nov162

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