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Characterization of KIR intermediate promoters reveals four promoter types associated with distinct expression patterns of KIR subtypes

The human KIR genes contain multiple promoters that control the process of gene activation and variegated expression of KIR on NK and T cells. Specific subfamilies of KIR genes have differences in the timing and tissue-specificity of expression: however, previous studies of the proximal KIR promoter...

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Detalles Bibliográficos
Autores principales: Li, Hongchuan, Wright, Paul W., McCullen, Matthew, Anderson, Stephen K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4724278/
https://www.ncbi.nlm.nih.gov/pubmed/26656451
http://dx.doi.org/10.1038/gene.2015.56