Human iPS cell model of type 3 long QT syndrome recapitulates drug-based phenotype correction

Long QT syndrome is a potentially life-threatening disease characterized by delayed repolarization of cardiomyocytes, QT interval prolongation in the electrocardiogram, and a high risk for sudden cardiac death caused by ventricular arrhythmia. The genetic type 3 of this syndrome (LQT3) is caused by...

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Detalles Bibliográficos
Autores principales: Malan, Daniela, Zhang, Miao, Stallmeyer, Birgit, Müller, Jovanca, Fleischmann, Bernd K., Schulze-Bahr, Eric, Sasse, Philipp, Greber, Boris
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2016
Materias:
Original Contribution
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4724360/
https://www.ncbi.nlm.nih.gov/pubmed/26803770
http://dx.doi.org/10.1007/s00395-016-0530-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4724360/
https://www.ncbi.nlm.nih.gov/pubmed/26803770
http://dx.doi.org/10.1007/s00395-016-0530-0

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