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Human iPS cell model of type 3 long QT syndrome recapitulates drug-based phenotype correction
Long QT syndrome is a potentially life-threatening disease characterized by delayed repolarization of cardiomyocytes, QT interval prolongation in the electrocardiogram, and a high risk for sudden cardiac death caused by ventricular arrhythmia. The genetic type 3 of this syndrome (LQT3) is caused by...
Autores principales: | Malan, Daniela, Zhang, Miao, Stallmeyer, Birgit, Müller, Jovanca, Fleischmann, Bernd K., Schulze-Bahr, Eric, Sasse, Philipp, Greber, Boris |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4724360/ https://www.ncbi.nlm.nih.gov/pubmed/26803770 http://dx.doi.org/10.1007/s00395-016-0530-0 |
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