Cargando…
Puzzling role of genetic risk factors in human longevity: “risk alleles” as pro-longevity variants
Complex diseases are major contributors to human mortality in old age. Paradoxically, many genetic variants that have been associated with increased risks of such diseases are found in genomes of long-lived people, and do not seem to compromise longevity. Here we argue that trade-off-like and condit...
| Autores principales: | , , , , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Springer Netherlands
2015
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4724477/ https://www.ncbi.nlm.nih.gov/pubmed/26306600 http://dx.doi.org/10.1007/s10522-015-9600-1 |