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A Review of the Mechanisms of Blood-Brain Barrier Permeability by Tissue-Type Plasminogen Activator Treatment for Cerebral Ischemia

Cerebrovascular homeostasis is maintained by the blood-brain barrier (BBB), which forms a mechanical and functional barrier between systemic circulation and the central nervous system (CNS). In patients with ischemic stroke, the recombinant tissue-type plasminogen activator (rt-PA) is used to accele...

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Detalles Bibliográficos
Autores principales:	Suzuki, Yasuhiro, Nagai, Nobuo, Umemura, Kazuo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2016
Materias:	Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4724711/ https://www.ncbi.nlm.nih.gov/pubmed/26834557 http://dx.doi.org/10.3389/fncel.2016.00002

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