Cargando…

Efficacy of Retigabine on Acute Limbic Seizures in Adult Rats

BACKGROUND AND PURPOSE: The efficacy of retigabine (RGB), a positive allosteric modulator of K+ channels indicated for adjunct treatment of partial seizures, was studied in two adult models of kainic acid (KA)-induced status epilepticus to determine it’s toleratbility. METHODS: Retigabine was admini...

Descripción completa

Detalles Bibliográficos
Autores principales:	Friedman, LK, Slomko, AM, Wongvravit, JP, Naseer, Z, Hu, S, Wan, WY, Ali, SS
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Korean Epilepsy Society 2015
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4724852/ https://www.ncbi.nlm.nih.gov/pubmed/26819936 http://dx.doi.org/10.14581/jer.15010

Ejemplares similares

Efficacy of Retigabine in Adjunctive Treatment of Partial Onset Seizures in Adults
por: Splinter, Michele Y.
Publicado: (2013)

Clinical utility of adjunctive retigabine in partial onset seizures in adults
por: Rejdak, Konrad, et al.
Publicado: (2012)

Beneficial effect of retigabine on memory in rats receiving ethanol
por: Zwierzyńska, Ewa, et al.
Publicado: (2020)

Profile of ezogabine (retigabine) and its potential as an adjunctive treatment for patients with partial-onset seizures
por: Weisenberg, Judith LZ, et al.
Publicado: (2011)

Acute retigabine‐induced effects on myelinated motor axons in amyotrophic lateral sclerosis
por: Sleutjes, Boudewijn T. H. M., et al.
Publicado: (2022)

European Survey of Prescriber Understanding of Risks Associated with Retigabine
por: Ishihara, Lianna, et al.
Publicado: (2015)

Survey of Physicians’ Understanding of Specific Risks Associated with Retigabine
por: Daniluk, Jerzy, et al.
Publicado: (2016)

Diversity of kindling of limbic seizures after lateral fluid percussion injury in the rat
por: Medel‐Matus, Jesús‐Servando, et al.
Publicado: (2021)

Clinical utility, safety, and tolerability of ezogabine (retigabine) in the treatment of epilepsy
por: Ciliberto, Michael A, et al.
Publicado: (2012)

Neuronal potassium channel openers in the management of epilepsy: role and potential of retigabine
por: Barrese, Vincenzo, et al.
Publicado: (2010)

The anticonvulsant retigabine is a subtype selective modulator of GABA (A) receptors
por: Treven, Marco, et al.
Publicado: (2015)

The anticonvulsant retigabine suppresses neuronal K(V)2-mediated currents
por: Stas, Jeroen I., et al.
Publicado: (2016)

Molecular Insights Into Binding and Activation of the Human KCNQ2 Channel by Retigabine
por: Garofalo, Barbara, et al.
Publicado: (2022)

Retigabine suppresses loss of force in mouse models of hypokalaemic periodic paralysis
por: Quiñonez, Marbella, et al.
Publicado: (2023)

Retigabine holds K(V)7 channels open and stabilizes the resting potential
por: Corbin-Leftwich, Aaron, et al.
Publicado: (2016)

A case report: retigabine induced oral mucosal dyspigmentation of the hard palate
por: Beacher, Nicholas G., et al.
Publicado: (2015)

Modifications of the Triaminoaryl Metabophore of Flupirtine and Retigabine Aimed at Avoiding Quinone Diimine Formation
por: Wurm, Konrad W., et al.
Publicado: (2022)

Electrically Induced Limbic Seizures: Preliminary Findings in a Rodent Model
por: Kowski, Alexander B, et al.
Publicado: (2015)

Gastaut-Geschwind Syndrome, Faciobrachial Dystonic Seizure, and Autoimmune Limbic Encephalitis
por: Benhamou, Ori-Michael J., et al.
Publicado: (2018)

Electro-mechanical coupling of KCNQ channels is a target of epilepsy-associated mutations and retigabine
por: Yang, Nien-Du, et al.
Publicado: (2022)

A Comment on Craig et al.: ‘‘Retigabine for the Adjunctive Treatment of Adults with Partial-Onset Seizures in Epilepsy with and without Secondary Generalization: A NICE Single Technology Appraisal’’
por: Holko, Przemysław, et al.
Publicado: (2013)

Limbic Seizures in Children, by G. Avanzini, A. Beaumanoir and L. Mira, Eds
por: Ferrie, C. D.
Publicado: (2002)

Intractable Seizures and Limbic Encephalitis, Unaccounted Complications of Type 1 Diabetes Autoimmunity
por: Madkhali, Mohammed A, et al.
Publicado: (2022)

Activation of voltage-gated KCNQ/Kv7 channels by anticonvulsant retigabine attenuates mechanical allodynia of inflammatory temporomandibular joint in rats
por: Xu, Wen, et al.
Publicado: (2010)

Physician and Pharmacist Understanding of the Risk of Urinary Retention with Retigabine (Ezogabine): A REMS Assessment Survey
por: Ishihara, Lianna, et al.
Publicado: (2015)

One drug-sensitive subunit is sufficient for a near-maximal retigabine effect in KCNQ channels
por: Yau, Michael C., et al.
Publicado: (2018)

Carba Analogues of Flupirtine and Retigabine with Improved Oxidation Resistance and Reduced Risk of Quinoid Metabolite Formation
por: Wurm, Konrad W., et al.
Publicado: (2022)

Retigabine, a K(v)7.2/K(v)7.3-Channel Opener, Attenuates Drug-Induced Seizures in Knock-In Mice Harboring Kcnq2 Mutations
por: Ihara, Yukiko, et al.
Publicado: (2016)

Limbic Encephalitis Manifesting as Selective Amnesia and Seizure-like Activity: A Case Report
por: Kim, So-Yeon, et al.
Publicado: (2018)

Combining endocannabinoids with retigabine for enhanced M-channel effect and improved K(V)7 subtype selectivity
por: Larsson, Johan E., et al.
Publicado: (2020)

Faciobrachio-crural dystonic seizures in LGI1 limbic encephalitis: A treatable cause of falls
por: Ismail, Fatme Seval, et al.
Publicado: (2015)

Relationship Between Seizure Frequency and Functional Abnormalities in Limbic Network of Medial Temporal Lobe Epilepsy
por: Jo, Hang Joon, et al.
Publicado: (2019)

Recurrent limbic seizures do not cause hippocampal neuronal loss: A prolonged laboratory study
por: Mathern, Gary W., et al.
Publicado: (2020)

Seizures in anti‐Hu–associated extra‐limbic encephalitis: Characterization of a unique disease manifestation
por: Budhram, Adrian, et al.
Publicado: (2022)

An In Vivo Electroencephalographic Analysis of the Effect of Riluzole against Limbic and Absence Seizure and Comparison with Glutamate Antagonists
por: Citraro, Rita, et al.
Publicado: (2023)

The Effects of the KCNQ Openers Retigabine and Flupirtine on Myotonia in Mammalian Skeletal Muscle Induced by a Chloride Channel Blocker
por: Su, Tzu-Rong, et al.
Publicado: (2012)

The Kv7 channel activator, retigabine, induces vasorelaxation via an endothelial-independent pathway in male mouse aorta
por: Namgoong, Hyun, et al.
Publicado: (2018)

Anterior thalamic nuclei lesions in rats disrupt markers of neural plasticity in distal limbic brain regions
por: Dumont, J.R., et al.
Publicado: (2012)

The Limbic System
por: Fulton, John F.
Publicado: (1953)

The limbic system
por: Rajmohan, V., et al.
Publicado: (2007)

Cannot write session to /tmp/vufind_sessions/sess_j158s43ot10ldnqsnjled6hoen