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Coagulase and Efb of Staphylococcus aureus Have a Common Fibrinogen Binding Motif

Coagulase (Coa) and Efb, secreted Staphylococcus aureus proteins, are important virulence factors in staphylococcal infections. Coa interacts with fibrinogen (Fg) and induces the formation of fibrin(ogen) clots through activation of prothrombin. Efb attracts Fg to the bacterial surface and forms a s...

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Detalles Bibliográficos
Autores principales:	Ko, Ya-Ping, Kang, Mingsong, Ganesh, Vannakambadi K., Ravirajan, Dharmanand, Li, Bin, Höök, Magnus
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society of Microbiology 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4725008/ https://www.ncbi.nlm.nih.gov/pubmed/26733070 http://dx.doi.org/10.1128/mBio.01885-15

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