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Herpesviral ICP0 Protein Promotes Two Waves of Heterochromatin Removal on an Early Viral Promoter during Lytic Infection

Herpesviruses must contend with host cell epigenetic silencing responses acting on their genomes upon entry into the host cell nucleus. In this study, we confirmed that unchromatinized herpes simplex virus 1 (HSV-1) genomes enter primary human foreskin fibroblasts and are rapidly subjected to assemb...

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Detalles Bibliográficos
Autores principales: Lee, Jennifer S., Raja, Priya, Knipe, David M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Microbiology 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4725016/
https://www.ncbi.nlm.nih.gov/pubmed/26758183
http://dx.doi.org/10.1128/mBio.02007-15

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