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TCR Signal Strength Alters T–DC Activation and Interaction Times and Directs the Outcome of Differentiation
The ability of CD4+ T cells to differentiate into effector subsets underpins their ability to shape the immune response and mediate host protection. During T cell receptor-induced activation of CD4+ T cells, both the quality and quantity of specific activatory peptide/MHC ligands have been shown to...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Frontiers Media S.A.
2016
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4725058/ https://www.ncbi.nlm.nih.gov/pubmed/26834747 http://dx.doi.org/10.3389/fimmu.2016.00006 |