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TimerQuant: a modelling approach to tandem fluorescent timer design and data interpretation for measuring protein turnover in embryos
Studies on signalling dynamics in living embryos have been limited by a scarcity of in vivo reporters. Tandem fluorescent protein timers provide a generic method for detecting changes in protein population age and thus provide readouts for signalling events that lead to changes in protein stability...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Company of Biologists Ltd
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4725204/ https://www.ncbi.nlm.nih.gov/pubmed/26603383 http://dx.doi.org/10.1242/dev.125971 |