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Identification of Escherichia coli ygaQ and rpmG as novel mitomycin C resistance factors implicated in DNA repair

Using the ASKA (A Complete Set of Escherichia coli K-12 ORF Archive) library for genome-wide screening of E. coli proteins we identified that expression of ygaQ and rpmG promotes mitomycin C resistance (MMC(R)). YgaQ mediated MMC(R) was independent of homologous recombination involving RecA or RuvAB...

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Detalles Bibliográficos
Autores principales: Bolt, Edward L., Jenkins, Tabitha, Russo, Valeria Moreira, Ahmed, Sharlene, Cavey, James, Cass, Simon D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4725251/
https://www.ncbi.nlm.nih.gov/pubmed/26704888
http://dx.doi.org/10.1042/BSR20150249