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PIK3R1 targeting by miR-21 suppresses tumor cell migration and invasion by reducing PI3K/AKT signaling and reversing EMT, and predicts clinical outcome of breast cancer

We have previously shown that dysregulation of miR-21 functioned as an oncomiR in breast cancer. The aim of the present study was to elucidate the mechanisms by which miR-21 regulate breast tumor migration and invasion. We applied pathway analysis on genome microarray data and target-predicting algo...

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Detalles Bibliográficos
Autores principales:	YAN, LI-XU, LIU, YAN-HUI, XIANG, JIAN-WEN, WU, QI-NIAN, XU, LEI-BO, LUO, XIN-LAN, ZHU, XIAO-LAN, LIU, CHAO, XU, FANG-PING, LUO, DONG-LAN, MEI, PING, XU, JIE, ZHANG, KE-PING, CHEN, JIE
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2015
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4725461/ https://www.ncbi.nlm.nih.gov/pubmed/26676464 http://dx.doi.org/10.3892/ijo.2015.3287

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