Acute Changes in Striatal Microstructure Predict the Development of Interferon-Alpha Induced Fatigue

BACKGROUND: Interferon-alpha (IFN-α) is a key mediator of antiviral immune responses used clinically for hepatitis C treatment. Though effective, IFN-α induces marked behavioral changes that, when severe, can appear indistinguishable from major depression. Curiously, fatigue and motivational impairm...

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Detalles Bibliográficos
Autores principales: Dowell, Nicholas G., Cooper, Ella A., Tibble, Jeremy, Voon, Valerie, Critchley, Hugo D., Cercignani, Mara, Harrison, Neil A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Archival Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4725575/
https://www.ncbi.nlm.nih.gov/pubmed/26169252
http://dx.doi.org/10.1016/j.biopsych.2015.05.015

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