Durable Control and Overall Survival Benefit with Focal Reirradiation in Cervical Cancer

Local recurrence following definitive chemoradiation in cervical cancer ranges from 5-18%. Currently, there are limited options available for patients recurring in para-aortic or iliac lymph nodes. We present two cases of reirradiation for non-central recurrences with intensity-modulated radiotherap...

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Detalles Bibliográficos
Autores principales: Amini, Arya, Sumner, Whitney, Fisher, Christine M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2015
Materias:
Radiation Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4725673/
https://www.ncbi.nlm.nih.gov/pubmed/26824003
http://dx.doi.org/10.7759/cureus.399
Descripción
Sumario:Local recurrence following definitive chemoradiation in cervical cancer ranges from 5-18%. Currently, there are limited options available for patients recurring in para-aortic or iliac lymph nodes. We present two cases of reirradiation for non-central recurrences with intensity-modulated radiotherapy (IMRT). Both patients achieved a complete response with manageable short-term toxicities and no late adverse effects with a follow-up of over one year and three years after reirradiation. While further follow-up is needed, IMRT is a feasible and safe option in cervical cancer patients with recurrent in-field failures involving the lymph nodes.

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