cAMP/PKA/CREB/GLT1 signaling involved in the antidepressant-like effects of phosphodiesterase 4D inhibitor (GEBR-7b) in rats

OBJECTIVES: GEBR-7b, a potential phosphodiesterase 4D inhibitor, has been shown to have memory-enhancing effects in rodents. However, it is still unknown whether GEBR-7b also has the antidepressant-like effects in rats. Herein, we examined the potential of GEBR-7b to attenuate depression-like behavi...

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Detalles Bibliográficos
Autores principales: Liu, Xu, Guo, Haibiao, Sayed, Mohammad Daud SOM, Lu, Yang, Yang, Ting, Zhou, Dongsheng, Chen, Zhongming, Wang, Haitao, Wang, Chuang, Xu, Jiangping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2016
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4725689/
https://www.ncbi.nlm.nih.gov/pubmed/26855578
http://dx.doi.org/10.2147/NDT.S90960

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