Bispecific Antibody Affords Complete Post-Exposure Protection of Mice from Both Ebola (Zaire) and Sudan Viruses

Filoviruses (Ebola and Marburg) cause severe hemorrhagic fever. There are five species of ebolavirus; among these, the Ebola (Zaire) and Sudan viruses (EBOV and SUDV, respectively) are highly pathogenic and have both caused recurring, large outbreaks. However, the EBOV and SUDV glycoprotein (GP) seq...

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Detalles Bibliográficos
Autores principales: Frei, Julia C., Nyakatura, Elisabeth K., Zak, Samantha E., Bakken, Russell R., Chandran, Kartik, Dye, John M., Lai, Jonathan R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4725817/
https://www.ncbi.nlm.nih.gov/pubmed/26758505
http://dx.doi.org/10.1038/srep19193

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