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Productive Entry of Foot-and-Mouth Disease Virus via Macropinocytosis Independent of Phosphatidylinositol 3-Kinase

Virus entry is an attractive target for therapeutic intervention. Here, using a combination of electron microscopy, immunofluorescence assay, siRNA interference, specific pharmacological inhibitors, and dominant negative mutation, we demonstrated that the entry of foot-and-mouth disease virus (FMDV)...

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Detalles Bibliográficos
Autores principales:	Han, Shi-Chong, Guo, Hui-Chen, Sun, Shi-Qi, Jin, Ye, Wei, Yan-Quan, Feng, Xia, Yao, Xue-Ping, Cao, Sui-Zhong, Xiang Liu, Ding, Liu, Xiang-Tao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4725844/ https://www.ncbi.nlm.nih.gov/pubmed/26757826 http://dx.doi.org/10.1038/srep19294

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