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DNA supercoiling, a critical signal regulating the basal expression of the lac operon in Escherichia coli

Escherichia coli lac repressor (LacI) is a paradigmatic transcriptional factor that controls the expression of lacZYA in the lac operon. This tetrameric protein specifically binds to the O1, O2 and O3 operators of the lac operon and forms a DNA loop to repress transcription from the adjacent lac pro...

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Detalles Bibliográficos
Autores principales:	Fulcrand, Geraldine, Dages, Samantha, Zhi, Xiaoduo, Chapagain, Prem, Gerstman, Bernard S., Dunlap, David, Leng, Fenfei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4725879/ https://www.ncbi.nlm.nih.gov/pubmed/26763930 http://dx.doi.org/10.1038/srep19243

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