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Wnt9a deficiency discloses a repressive role of Tcf7l2 on endocrine differentiation in the embryonic pancreas

Transcriptional and signaling networks establish complex cross-regulatory interactions that drive cellular differentiation during development. Using microarrays we identified the gene encoding the ligand Wnt9a as a candidate target of Neurogenin3, a basic helix-loop-helix transcription factor that f...

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Detalles Bibliográficos
Autores principales: Pujadas, G., Cervantes, S., Tutusaus, A., Ejarque, M., Sanchez, L., García, A., Esteban, Y., Fargas, L., Alsina, B., Hartmann, C., Gomis, R., Gasa, R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4725895/
https://www.ncbi.nlm.nih.gov/pubmed/26771085
http://dx.doi.org/10.1038/srep19223