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Stabilizing Off-pathway Oligomers by Polyphenol Nanoassemblies for IAPP Aggregation Inhibition

Experimental studies have shown that many naturally occurring polyphenols have inhibitory effect on the aggregation of several proteins. Here, we use discrete molecular dynamics (DMD) simulations and high-throughput dynamic light scattering (DLS) experiments to study the anti-aggregation effects of...

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Detalles Bibliográficos
Autores principales:	Nedumpully-Govindan, Praveen, Kakinen, Aleksandr, Pilkington, Emily H., Davis, Thomas P., Chun Ke, Pu, Ding, Feng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4725907/ https://www.ncbi.nlm.nih.gov/pubmed/26763863 http://dx.doi.org/10.1038/srep19463

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