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Regulation of Asymmetric Division by Atypical Protein Kinase C Influences Early Specification of CD8(+) T Lymphocyte Fates
Naïve CD8(+) T lymphocytes responding to microbial pathogens give rise to effector T cells that provide acute defense and memory T cells that provide long-lived immunity. Upon activation, CD8(+) T lymphocytes can undergo asymmetric division, unequally distributing factors to the nascent daughter cel...
Autores principales: | Metz, Patrick J., Lopez, Justine, Kim, Stephanie H., Akimoto, Kazunori, Ohno, Shigeo, Chang, John T. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4725917/ https://www.ncbi.nlm.nih.gov/pubmed/26765121 http://dx.doi.org/10.1038/srep19182 |
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