Parity and All-cause Mortality in Women and Men: A Dose-Response Meta-Analysis of Cohort Studies

To quantitatively assess the association between parity and all-cause mortality, we conducted a meta-analysis of cohort studies. Relevant reports were identified from PubMed and Embase databases. Cohort studies with relative risks (RRs) and 95% confidence intervals (CIs) of all-cause mortality in th...

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Autores principales: Zeng, Yun, Ni, Ze-min, Liu, Shu-yun, Gu, Xue, Huang, Qin, Liu, Jun-an, Wang, Qi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4725925/
https://www.ncbi.nlm.nih.gov/pubmed/26758416
http://dx.doi.org/10.1038/srep19351
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author Zeng, Yun
Ni, Ze-min
Liu, Shu-yun
Gu, Xue
Huang, Qin
Liu, Jun-an
Wang, Qi
author_facet Zeng, Yun
Ni, Ze-min
Liu, Shu-yun
Gu, Xue
Huang, Qin
Liu, Jun-an
Wang, Qi
author_sort Zeng, Yun
collection PubMed
description To quantitatively assess the association between parity and all-cause mortality, we conducted a meta-analysis of cohort studies. Relevant reports were identified from PubMed and Embase databases. Cohort studies with relative risks (RRs) and 95% confidence intervals (CIs) of all-cause mortality in three or more categories of parity were eligible. Eighteen articles with 2,813,418 participants were included. Results showed that participants with no live birth had higher risk of all-cause mortality (RR= 1.19, 95% CI = 1.03–1.38; I(2) = 96.7%, P < 0.001) compared with participants with one or more live births. Nonlinear dose-response association was found between parity and all-cause mortality (P for non-linearity < 0.0001). Our findings suggest that moderate-level parity is inversely associated with all-cause mortality.
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spelling pubmed-47259252016-01-28 Parity and All-cause Mortality in Women and Men: A Dose-Response Meta-Analysis of Cohort Studies Zeng, Yun Ni, Ze-min Liu, Shu-yun Gu, Xue Huang, Qin Liu, Jun-an Wang, Qi Sci Rep Article To quantitatively assess the association between parity and all-cause mortality, we conducted a meta-analysis of cohort studies. Relevant reports were identified from PubMed and Embase databases. Cohort studies with relative risks (RRs) and 95% confidence intervals (CIs) of all-cause mortality in three or more categories of parity were eligible. Eighteen articles with 2,813,418 participants were included. Results showed that participants with no live birth had higher risk of all-cause mortality (RR= 1.19, 95% CI = 1.03–1.38; I(2) = 96.7%, P < 0.001) compared with participants with one or more live births. Nonlinear dose-response association was found between parity and all-cause mortality (P for non-linearity < 0.0001). Our findings suggest that moderate-level parity is inversely associated with all-cause mortality. Nature Publishing Group 2016-01-13 /pmc/articles/PMC4725925/ /pubmed/26758416 http://dx.doi.org/10.1038/srep19351 Text en Copyright © 2016, Macmillan Publishers Limited http://creativecommons.org/licenses/by/4.0/ This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/
spellingShingle Article
Zeng, Yun
Ni, Ze-min
Liu, Shu-yun
Gu, Xue
Huang, Qin
Liu, Jun-an
Wang, Qi
Parity and All-cause Mortality in Women and Men: A Dose-Response Meta-Analysis of Cohort Studies
title Parity and All-cause Mortality in Women and Men: A Dose-Response Meta-Analysis of Cohort Studies
title_full Parity and All-cause Mortality in Women and Men: A Dose-Response Meta-Analysis of Cohort Studies
title_fullStr Parity and All-cause Mortality in Women and Men: A Dose-Response Meta-Analysis of Cohort Studies
title_full_unstemmed Parity and All-cause Mortality in Women and Men: A Dose-Response Meta-Analysis of Cohort Studies
title_short Parity and All-cause Mortality in Women and Men: A Dose-Response Meta-Analysis of Cohort Studies
title_sort parity and all-cause mortality in women and men: a dose-response meta-analysis of cohort studies
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4725925/
https://www.ncbi.nlm.nih.gov/pubmed/26758416
http://dx.doi.org/10.1038/srep19351
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