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Quantitative analysis of intrinsic and extrinsic factors in the aggregation mechanism of Alzheimer-associated Aβ-peptide

Disease related mutations and environmental factors are key determinants of the aggregation mechanism of the amyloid-β peptide implicated in Alzheimer's disease. Here we present an approach to investigate these factors through acquisition of highly reproducible data and global kinetic analysis...

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Detalles Bibliográficos
Autores principales:	Meisl, Georg, Yang, Xiaoting, Frohm, Birgitta, Knowles, Tuomas P. J., Linse, Sara
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4725935/ https://www.ncbi.nlm.nih.gov/pubmed/26758487 http://dx.doi.org/10.1038/srep18728

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