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Azilsartan Improves Salt Sensitivity by Modulating the Proximal Tubular Na(+)-H(+) Exchanger-3 in Mice
A potent angiotensin II type-1 receptor blocker, azilsartan, has been reported to reduce blood pressure more effectively than candesartan. Interestingly, azilsartan can also restore the circadian rhythm of blood pressure. We hypothesized that azilsartan could also improve salt sensitivity; thus, we...
Autores principales: | Hatanaka, Masaki, Kaimori, Jun-Ya, Yamamoto, Satoko, Matsui, Isao, Hamano, Takayuki, Takabatake, Yoshitsugu, Ecelbarger, Carolyn M., Takahara, Shiro, Isaka, Yoshitaka, Rakugi, Hiromi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4725961/ https://www.ncbi.nlm.nih.gov/pubmed/26807585 http://dx.doi.org/10.1371/journal.pone.0147786 |
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