Cargando…

Cardiac Dysfunction in the BACHD Mouse Model of Huntington’s Disease

While Huntington’s disease (HD) is classified as a neurological disorder, HD patients exhibit a high incidence of cardiovascular events leading to heart failure and death. In this study, we sought to better understand the cardiovascular phenotype of HD using the BACHD mouse model. The age-related de...

Descripción completa

Detalles Bibliográficos
Autores principales:	Schroeder, Analyne M., Wang, Huei Bin, Park, Saemi, Jordan, Maria C., Gao, Fuying, Coppola, Giovanni, Fishbein, Michael C., Roos, Kenneth P., Ghiani, Cristina A., Colwell, Christopher S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4725962/ https://www.ncbi.nlm.nih.gov/pubmed/26807590 http://dx.doi.org/10.1371/journal.pone.0147269

Ejemplares similares

Baroreceptor reflex dysfunction in the BACHD mouse model of Huntington’s disease.
por: Schroeder, Analyne M., et al.
Publicado: (2011)

Targeted Genetic Reduction of Mutant Huntingtin Lessens Cardiac Pathology in the BACHD Mouse Model of Huntington's Disease
por: Park, Saemi, et al.
Publicado: (2021)

Sex Differences in Circadian Dysfunction in the BACHD Mouse Model of Huntington’s Disease
por: Kuljis, Dika A., et al.
Publicado: (2016)

Sex Differences in Sleep Phenotypes in the BACHD Mouse Model of Huntington’s Disease
por: Chiem, Emily, et al.
Publicado: (2023)

Dietary ketosis improves circadian dysfunction as well as motor symptoms in the BACHD mouse model of Huntington’s disease
por: Whittaker, Daniel S., et al.
Publicado: (2022)

Neurocardiovascular deficits in the Q175 mouse model of Huntington's disease
por: Cutler, Tamara S., et al.
Publicado: (2017)

Do Disruptions in the Circadian Timing System Contribute to Autonomic Dysfunction in Huntington’s Disease?
por: Park, Saemi, et al.
Publicado: (2019)

Effects of mutant huntingtin inactivation on Huntington disease‐related behaviours in the BACHD mouse model
por: Cheong, Rachel Y., et al.
Publicado: (2021)

Blue light therapy improves circadian dysfunction as well as motor symptoms in two mouse models of Huntington's disease
por: Wang, Huei-Bin, et al.
Publicado: (2017)

BACHD Mice Recapitulate the Striatal Parvalbuminergic Interneuron Loss Found in Huntington’s Disease
por: Rallapalle, Vyshnavi, et al.
Publicado: (2021)

Environment-dependent striatal gene expression in the BACHD rat model for Huntington disease
por: Novati, Arianna, et al.
Publicado: (2018)

Metabolic and behavioral effects of mutant huntingtin deletion in Sim1 neurons in the BACHD mouse model of Huntington’s disease
por: Soylu-Kucharz, Rana, et al.
Publicado: (2016)

Structural and functional features of medium spiny neurons in the BACHDΔN17 mouse model of Huntington’s Disease
por: Goodliffe, Joseph, et al.
Publicado: (2020)

Reversal Learning and Associative Memory Impairments in a BACHD Rat Model for Huntington Disease
por: Abada, Yah-se K., et al.
Publicado: (2013)

Reduced Motivation in the BACHD Rat Model of Huntington Disease Is Dependent on the Choice of Food Deprivation Strategy
por: Jansson, Erik Karl Håkan, et al.
Publicado: (2014)

The Alteration of Emotion Regulation Precedes the Deficits in Interval Timing in the BACHD Rat Model for Huntington Disease
por: Garces, Daniel, et al.
Publicado: (2018)

Effects of Deletion of Mutant Huntingtin in Steroidogenic Factor 1 Neurons on the Psychiatric and Metabolic Phenotype in the BACHD Mouse Model of Huntington Disease
por: Baldo, Barbara, et al.
Publicado: (2014)

The BACHD Rat Model of Huntington Disease Shows Signs of Fronto-Striatal Dysfunction in Two Operant Conditioning Tests of Short-Term Memory
por: Clemensson, Erik Karl Håkan, et al.
Publicado: (2017)

The BACHD Rat Model of Huntington Disease Shows Specific Deficits in a Test Battery of Motor Function
por: Manfré, Giuseppe, et al.
Publicado: (2017)

Differential Cellular Balance of Olfactory and Vomeronasal Epithelia in a Transgenic BACHD Rat Model of Huntington’s Disease
por: Krysewski, Lina-Marielle, et al.
Publicado: (2022)

Structural and molecular myelination deficits occur prior to neuronal loss in the YAC128 and BACHD models of Huntington disease
por: Teo, Roy Tang Yi, et al.
Publicado: (2016)

Further investigation of phenotypes and confounding factors of progressive ratio performance and feeding behavior in the BACHD rat model of Huntington disease
por: Clemensson, Erik Karl Håkan, et al.
Publicado: (2017)

High-Throughput Sequencing of BACHD Mice Reveals Upregulation of Neuroprotective miRNAs at the Pre-Symptomatic Stage of Huntington’s Disease
por: Olmo, Isabella G., et al.
Publicado: (2021)

Assessment of Motor Function, Sensory Motor Gating and Recognition Memory in a Novel BACHD Transgenic Rat Model for Huntington Disease
por: Abada, Yah-se K., et al.
Publicado: (2013)

Correction: Further investigation of phenotypes and confounding factors of progressive ratio performance and feeding behavior in the BACHD rat model of Huntington disease
por: Clemensson, Erik Karl Håkan, et al.
Publicado: (2019)

Time-Restricted Feeding Improves Circadian Dysfunction as well as Motor Symptoms in the Q175 Mouse Model of Huntington’s Disease
por: Wang, Huei-Bin, et al.
Publicado: (2018)

A small molecule p75(NTR) ligand normalizes signalling and reduces Huntington’s disease phenotypes in R6/2 and BACHD mice
por: Simmons, Danielle A., et al.
Publicado: (2016)

Sexual behavior and testis morphology in the BACHD rat model
por: Novati, Arianna, et al.
Publicado: (2018)

Expression of Mutant Huntingtin in Leptin Receptor-Expressing Neurons Does Not Control the Metabolic and Psychiatric Phenotype of the BACHD Mouse
por: Lundh, Sofia Hult, et al.
Publicado: (2012)

Possible use of a H3R antagonist for the management of nonmotor symptoms in the Q175 mouse model of Huntington's disease
por: Whittaker, Daniel S., et al.
Publicado: (2017)

Dysfunction of the CNS-Heart Axis in Mouse Models of Huntington's Disease
por: Mielcarek, Michal, et al.
Publicado: (2014)

Nascent polypeptide-Associated Complex and Signal Recognition Particle have cardiac-specific roles in heart development and remodeling
por: Schroeder, Analyne M., et al.
Publicado: (2022)

BACHD rats expressing full-length mutant huntingtin exhibit differences in social behavior compared to wild-type littermates
por: Manfré, Giuseppe, et al.
Publicado: (2018)

Sleep/Wake Disruption in a Mouse Model of BLOC-1 Deficiency
por: Lee, Frank Y., et al.
Publicado: (2018)

Olfactory Dysfunction in Huntington’s Disease
por: Patino, Jorge, et al.
Publicado: (2021)

Temporal Characterization of Behavioral and Hippocampal Dysfunction in the YAC128 Mouse Model of Huntington’s Disease
por: de Paula Nascimento-Castro, Cristine, et al.
Publicado: (2022)

Sexually Dimorphic Serotonergic Dysfunction in a Mouse Model of Huntington's Disease and Depression
por: Renoir, Thibault, et al.
Publicado: (2011)

Early dysfunction and progressive degeneration of the subthalamic nucleus in mouse models of Huntington's disease
por: Atherton, Jeremy F, et al.
Publicado: (2016)

Rosiglitazone Ameliorates Cardiac and Skeletal Muscle Dysfunction by Correction of Energetics in Huntington’s Disease
por: Tomczyk, Marta, et al.
Publicado: (2022)

Genomic Analysis Reveals Disruption of Striatal Neuronal Development and Therapeutic Targets in Human Huntington’s Disease Neural Stem Cells
por: Ring, Karen L., et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_rs754pohklpautn66iorge1s3o