Cargando…
miRNA-378 reverses chemoresistance to cisplatin in lung adenocarcinoma cells by targeting secreted clusterin
Cisplatin resistance is a major obstacle in the treatment of NSCLC, and its mechanism has not been fully elucidated. The objectives of the study were to determine the role of miR-378 in the sensitivity of lung adenocarcinoma cells to cisplatin (cDDP) and its working mechanism. With TargetScan and lu...
Autores principales: | Chen, Xuesong, Jiang, Ying, Huang, Zheping, Li, Dandan, Chen, Xiaodi, Cao, Mengru, Meng, Qingwei, Pang, Hui, Sun, Lichun, Zhao, Yanbin, Cai, Li |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4725983/ https://www.ncbi.nlm.nih.gov/pubmed/26781643 http://dx.doi.org/10.1038/srep19455 |
Ejemplares similares
-
EHD1 confers resistance to cisplatin in non-small cell lung cancer by regulating intracellular cisplatin concentrations
por: Gao, Jing, et al.
Publicado: (2016) -
Clusterin: a key player in cancer chemoresistance and its inhibition
por: Koltai, Tomas
Publicado: (2014) -
TGM2 knockdown reverses cisplatin chemoresistance in osteosarcoma
por: Li, Cuiyun, et al.
Publicado: (2018) -
HMGB1 induction of clusterin creates a chemoresistant niche in human prostate tumor cells
por: Zhou, Junmin, et al.
Publicado: (2015) -
Secreted clusterin (sCLU) regulates cell
proliferation and chemosensitivity to cisplatin by modulating ERK1/2 signals in human
osteosarcoma cells
por: Huang, Hai, et al.
Publicado: (2014)